Genotypic discrepancies arising from imputation
نویسندگان
چکیده
منابع مشابه
Genotypic discrepancies arising from imputation
The ideal genetic analysis of family data would include whole genome sequence on all family members. A strategy of combining sequence data from a subset of key individuals with inexpensive, genome-wide association study (GWAS) chip genotypes on all individuals to infer sequence level genotypes throughout the families has been suggested as a highly accurate alternative. This strategy was followe...
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process of machine learning and data mining when certain values are missed. Among extant imputation techniques, kNN imputation algorithm is the best one as it is a model free and efficient compared with other methods. However, the value of k must be chosen properly in using kNN imputation. In particular, when some nearest neighbors are far from a missing data, the kNN imputation algorithms are ...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2014
ISSN: 1753-6561
DOI: 10.1186/1753-6561-8-s1-s17